Am80‐ GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality
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منابع مشابه
Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality
Neutrophils generated by granulocyte colony-stimulating factor (GCSF) are functionally immature and, consequently, cannot effectively reduce infection and infection-related mortality in cancer chemotherapy-induced neutropenia (CCIN). Am80, a retinoic acid (RA) agonist that enhances granulocytic differentiation by selectively activating transcription factor RA receptor alpha (RARα), alternativel...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2016
ISSN: 1757-4676,1757-4684
DOI: 10.15252/emmm.201606434